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Roaccutan® (Isotretinoin)
Accutan is used in the treatment of acne. Four to five months ofisotretinoin treatment usually leads to clearing of acne for one yearor more after the medicine is stopped.
Most other acne-controlling medicines are antibacterial agents, which are effective only if the medicine is used daily.
Isotretinoin has significant side effects: (percentages are the ratioof people who received the side-effect). Chapped lips 90% , dry skinand itching 80% - the use of daily alpha hydroxacids will help preventthis side effect. Dryness of nose, mild nosebleed 80%, Irritation ofthe eyelids and eyes 40% - Vitamin E 400 IU each day may lessen thisside effect. Joint and muscle pains 15%, Temporary hair thinning 10%,Rash 7%, Intestinal symptoms 5%, Urinary symptoms 5%, Headache 5%,Increased sensitivity to sunburn 5%, Decreased night vision <1%,Depression, thoughts of suicide <1%.
Isotretinoin may increase the level of blood fats, sometimes to riskylevels. Occasionally it may affect the liver. That is why regular bloodtests are necessary when you are taking isotretinoin. These tests mustbe done when you have fasted for 12 hours (no breakfast), so that theblood fat determinations are reliable. A baseline blood chemistry testis established before patients start isotretinoin.
Isotretinoin (Accutan, Roaccutan) is a form of vitamin A. It reduces the amount of oil released by oil glands in your skin, and helps your skin renew itself more quickly.
Isotretinoin is used to treat severe nodular acne. It is usually given after other acne medicines or antibiotics have been tried without successful treatment of symptoms.
Isotretinoin can cause severe, life-threatening birth defects if the mother takes the medication during pregnancy. Even one dose of isotretinoin can cause major birth defects of the baby's ears, eyes, face, skull, heart, and brain. Never use isotretinoin if you are pregnant.
Women of child-bearing potential must agree in writing to use two specific forms of birth control and have regular pregnancy tests before, during, and after taking isotretinoin. Unless you have had a total hysterectomy or have been in menopause for at least a year, you are considered to be of child-bearing potential.
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